The Future of Medical Research and Treatment: Impacts of the Pandemic

July 
26
, 
2019
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Clear your calendar - It's going down! Splash Blocks kicks off on April 21st, and you're invited to take part in the festivities. Splash HQ (122 W 26th St) is our meeting spot for a night of fun and excitement. Come one, come all, bring a guest, and hang loose. This is going to be epic!

Clear your calendar - It's going down! Splash Blocks kicks off on April 21st, and you're invited to take part in the festivities. Splash HQ (122 W 26th St) is our meeting spot for a night of fun and excitement. Come one, come all, bring a guest, and hang loose. This is going to be epic!

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Clear your calendar - It's going down! Splash Blocks kicks off on April 21st, and you're invited to take part in the festivities. Splash HQ (122 W 26th St) is our meeting spot for a night of fun and excitement. Come one, come all, bring a guest, and hang loose. This is going to be epic!

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The Future of Medical Research and Treatment: Impacts of the Pandemic

Join us Via Zoom for a Virtual Conference

Wednesday
, 
March 
18
, 
2020
8:00am
–
9:30am

LA Plaza Village Apartments, 555 North Spring Street, Los Angeles CA, 90012

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Keynote Speaker

Patrick Soon-Shiong, M.D.

Chairman & chief executive officer

LNantWorks

Patrick Soon-Shiong, M.D., a physician, surgeon, scientist, inventor, technologist and philanthropist, has devoted his career to understanding the fundamental biology driving life-threatening diseases and translating these insights into medical innovations with global impact.

 

He serves as Chairman and Chief Executive Officer of NantWorks, an ecosystem of companies with deep understandings in a wide variety of complex industries, from medical science to physics, from data to AI and from communications to mobility. 

 

Dr. Soon-Shiong was born in Port Elizabeth South Africa and received his medical degree at the University of the Witwatersrand, Johannesburg in 1975. He was the first Chinese intern granted permission to serve his internship at the Johannesburg General Hospital during the period of apartheid. Following a period in the TB clinics in East London, he left to continue his training as a surgeon at University of California, Los Angeles (UCLA). He was appointed Assistant Professor of Surgery and Assistant Professor of Medicine at UCLA, led the development of the California NanoSystems Institute and received support from NASA and NIST to develop next-generation biological materials. While at UCLA, he served as Executive Director of the UCLA Wireless Health Institute and a Professor of Microbiology, Immunology & Molecular Genetics and Professor of Bioengineering at the California NanoSystems Institute of UCLA. He currently is an Adjunct Professor of Surgery at the University of California, Los Angeles (UCLA), a visiting Professor at the Imperial College of London. Dr. Soon-Shiong currently sits on the Board of Councilors at the University of Southern California (USC) Viterbi School of Engineering.

 

Over the course of Dr. Soon-Shiong’s career, he has pioneered novel therapies for both diabetes and cancer, including the revolutionary drug Abraxane, a protein nanoparticle, which has received U.S. Food and Drug Administration (FDA) approval for the treatment of metastatic breast cancer, lung cancer and advanced pancreatic cancer in both the U.S. and E.U., published more than 100 scientific papers, and has been granted more than 400 patents worldwide for groundbreaking advancements spanning myriad fields of technology and medicine.

 

As a surgeon, Dr. Soon-Shiong performed the world’s first encapsulated human islet transplant, the first engineered islet cell transplant and the first pig-to-man islet cell transplant in patients with diabetes.

 

Dr. Soon-Shiong’s path to cancer research began while doing research for the National Aeronautics and Space Administration (NASA) that involved harnessing stem cells to make insulin. In 1991, he founded a biotechnology company to develop a novel nanoparticle anti-cancer drug with the concept of using “the tumors biology against itself.” 

 

From 1996 to 2010, Dr. Soon-Shiong served as Founder, Chairman and CEO of two global pharmaceutical companies: American Pharmaceutical Partners and Abraxis BioScience. It was during Dr. Soon-Shiong’s tenure at Abraxis that the company manufactured the world’s first protein nanoparticle drug for breast, lung and pancreatic cancer—Abraxane. In 2008, Dr. Soon-Shiong sold American Pharmaceutical Partners to Fresenius for approximately $4.6 billion and in 2010, sold Abraxis BioScience to Celgene for approximately $3.8 billion.

 

Following the sale of these two companies in 2010, Dr. Soon-Shiong established NantWorks, LLC, an ecosystem of companies with deep understandings in a wide variety of complex industries, from science to data, communication and mobility. The mission of NantWorks is to develop technologies which would have global impact on life-threatening diseases such as cancer and pandemic infectious diseases. Under the NantWorks umbrella, Soon-Shiong serves as Executive Chairman of NantKwest, a Nasdaq-listed immunotherapy company focusing on natural killer cells; Chairman and CEO of ImmunityBio, Inc., a biotechnology company focusing on vaccines and immunotherapy for cancer and infectious diseases; Chairman and CEO of NantHealth, a Nasdaq listed transformational healthcare company converging biomolecular medicine and bioinformatics with deep learning AI to empower physicians, patients, payers, pharma and researchers to transcend the traditional barriers of today's healthcare system; Chairman of NantEnergy, a privately-held company accelerating the worldwide transformation to clean, reliable energy disrupting industrial scale methods of heat production, cement and plastics manufacturing; and Owner and Executive Chairman of California Times, publisher of two of the state’s largest newspapers, the Los Angeles Times and The San Diego Union-Tribune. 

 

In January 2016, Dr. Soon-Shiong announced the formation of Cancer Breakthroughs 2020, a comprehensive collaboration of researchers, insurers, academic institutions and pharmaceutical companies to accelerate the potential of combination immunotherapy in the treatment of cancer. 

 

The Cancer Breakthroughs 2020 initiative has a goal of originating Phase 2 and 3 trials of the Nant Cancer Vaccine in multiple tumor types. By 2020, Dr. Soon-Shiong’s team have initiated over 17 investigational new drug (IND) applications demonstrating the safety and efficacy of first-in-human novel biological fusion proteins and adenovirus vaccines with complete remissions in multiple tumor types including metastatic pancreatic cancer, metastatic head & neck cancer, metastatic triple negative breast cancer, and merkel cell carcinoma.  

 

Dr. Soon-Shiong is Chairman of the Chan Soon-Shiong Family Foundation and of the Chan Soon-Shiong Institute of Molecular Medicine, a nonprofit medical research organization. In May 2017, he was appointed by House Speaker Paul Ryan to the Health Information Technology Advisory Committee, a committee established by the 21st Century Cures Act that will advise the President and his administration on health IT policy and will tackle issues with healthcare interoperability and privacy and security, while working with key stakeholders to create standards in these areas.

 

In April 2016, Dr. Soon-Shiong received the Franklin Institute Award for his visionary leadership and commitment to advancing medical and scientific research and bringing new treatment options to people with cancer. Dr. Soon-Shiong was also honored at the Vatican with the Pontifical Key Visionary Award in April 2016, which recognizes “medical innovators who change the course of history and reduce suffering on a global scale by blending visionary thinking with real action.” The Friends of the National Library of Medicine has also honored him with their Distinguished Medical Science Award. 

 

In June 2017, the Smithsonian Institute honored his work by placing Abraxane in the permanent exhibit at Smithsonian’s National Museum of American History. 

 

In June 2018, Dr. Soon-Shiong completed the purchase of the Los Angeles Times, San Diego Union-Tribune and publications under the California News Group.

 

In 2020, Dr. Soon-Shiong and his scientific team devoted their resources and scientific expertise to the development of a vaccine to address the COVID-19 pandemic. Utilizing their expertise in treating cancer, Dr. Soon-Shiong and his team took the novel approach of developing a vaccine that would induce both antibodies and T cells to clear the virus. To date, this vaccine construct which includes both the Spike (S) and Nucleocapsid (N) protein is the first-in-human subcutaneous formulation to demonstrate antibody as well as T cell immune response. In the US BARDA Operation Warp Speed sponsored Non-Human Primate (NHP) challenge study, the vaccine both as an orally room temperature stable capsule as well as a subcutaneous formulation showed 100% protection against SARS-CoV-2 challenge in all animals tested. The subcutaneous formulation has initiated clinical trials and demonstrated no serious adverse events to date. The sublingual and oral formulation will initiate Phase 1 trials shortly. With the evolution of the virus and mutations in Spike, the N + S T cell vaccine developed by ImmunityBio could provide a solution to the rapidly mutating SARS-CoV-2 virus.  By developing a room temperature oral form of the vaccine, global distribution, especially to developing countries could be achieved.

 

Born and raised during apartheid in South Africa, Dr. Soon-Shiong resides in Los Angeles California and is a citizen of the United States.

KEYNOTE SPEAKER


Patrick Soon-Shiong, M.D.

CHAIRMAN & CHIEF EXECUTIVE OFFICER


NantWorks

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Speakers

Nancy Ander

Deputy director

office of sustainability

california department of general services

 

Amisha rai

Managing director

advanced energy economy
 

 

Matt petersen

president & ceo

Los angeles cleantech incubator (laci)

 

Nancy Sutley

Chief Sustainability Officer

Los Angeles Department Of Water & Power

Dr. Fynnwin Prager

Assistant Professor

Public Administration California State University Dominguez Hills
 

 

judy kruger - moderator

senior director of

strategic initiatives

los angeles county economic development corporation

 

PANELISTS

Stephanie Hsieh, , J.D., M.B.A. 

Executive Director

Biocom LA

Speaking on:

Bugs

Jeff Golden, M.D.

Director

Vice Dean, Research and Graduate Education

the Burns and Allen Research Institute

Cedars Sinai Medical Center

Speaking on:

Headphones that will change your life

Jon thomas, Ph.D., J.D

Chairman


California Institute for Regenerative Medicine


Speaking on:

Entrepreneurship: The rights and the wrongs

why attend?

In 2020 the bioscience industry faced perhaps its greatest challenge in modern history.

Leonard Bernstein,

Splash, Composer

From initial research, to testing potential cures and preventions, and now revolutionizing supply chains and distribution, the industry made front page news weekly while both experts and the general public followed developments like their lives depended on it – and they did.  

The past year’s innovations have accelerated the growth of an already burgeoning industry, with bioscience activity in Los Angeles County on the rise long before the pandemic. Medical research is constantly being impacted by new technology, and the typical process of FDA approval and access progress more rapidly each day.

 

We’ll analyze how the events of the past year sped up growth of the industry and what long-term impacts the pandemic will have on medical treatment development, approval, and distribution.



During these unprecedented times, the future can be intimidating, but the bioscience industry provides a progressive pathway to developing treatments and cures across the disease spectrum.

 

The LAEDC is focusing on timely research to provide updated regional insights to inform the bioscience stakeholders and decisionmakers about the state of the industry including challenges, opportunities, and how a year with the pandemic will affect future growth.

PANELISTS

R. Harrison

Clear your calendar - It's going down! Splash Blocks kicks off on April 21st, and you're invited to take part in the festivities. Splash HQ (122 W 26th St) is our meeting spot for a night of fun and excitement. Come one, come all, bring a guest, and hang loose. This is going to be epic!

Clear your calendar - It's going down! Splash Blocks kicks off on April 21st, and you're invited to take part in the festivities. Splash HQ (122 W 26th St) is our meeting spot for a night of fun and excitement. Come one, come all, bring a guest, and hang loose. This is going to be epic!

Speaker Block #3

R. Harrison

Clear your calendar - It's going down! Splash Blocks kicks off on April 21st, and you're invited to take part in the festivities. Splash HQ (122 W 26th St) is our meeting spot for a night of fun and excitement. Come one, come all, bring a guest, and hang loose. This is going to be epic!

Clear your calendar - It's going down! Splash Blocks kicks off on April 21st, and you're invited to take part in the festivities. Splash HQ (122 W 26th St) is our meeting spot for a night of fun and excitement. Come one, come all, bring a guest, and hang loose. This is going to be epic!

R. Harrison

Clear your calendar - It's going down! Splash Blocks kicks off on April 21st, and you're invited to take part in the festivities. Splash HQ (122 W 26th St) is our meeting spot for a night of fun and excitement. Come one, come all, bring a guest, and hang loose. This is going to be epic!

Clear your calendar - It's going down! Splash Blocks kicks off on April 21st, and you're invited to take part in the festivities. Splash HQ (122 W 26th St) is our meeting spot for a night of fun and excitement. Come one, come all, bring a guest, and hang loose. This is going to be epic!

Speaker Block #3

R. Harrison

Clear your calendar - It's going down! Splash Blocks kicks off on April 21st, and you're invited to take part in the festivities. Splash HQ (122 W 26th St) is our meeting spot for a night of fun and excitement. Come one, come all, bring a guest, and hang loose. This is going to be epic!

Clear your calendar - It's going down! Splash Blocks kicks off on April 21st, and you're invited to take part in the festivities. Splash HQ (122 W 26th St) is our meeting spot for a night of fun and excitement. Come one, come all, bring a guest, and hang loose. This is going to be epic!

Text Block #12

LAEDC

Los Angeles County Economic Development Corporation (LAEDC) was founded in 1981 as a nonprofit, public-benefit organization to harness the power of private sector in collaboration with L.A. County, to guide economic development and create more widely shared prosperity.


LAEDC collaborates with all stakeholders in the region including education, business, and government. We do this by fostering growth of well-paying jobs, and by preparing our residents

for those opportunities. We make decisions based on a triple bottom line: Economy, Equity, Environment.

 

More can be found on our website at https://laedc.org/.

 Future forums

LAEDC’s Future Forums series of four events each year is be an opportunity to take a deep dive into burgeoning industries like virtual medicine, cybersecurity, digital entertainment, the green economy, and others.


As technological innovation and globalization take the economy in new directions, this region is destined to be an incubator for business opportunities that were only an entrepreneur’s dream a few years ago.


Each Future Forum will be your chance to learn about the trends ahead, the workforce demands that will be required and, most importantly, the opportunities that will be available tomorrow.

Text Block #9

In Lieu of Registration Fees: As the world continues to come t terms with the COVID-19 pandemic, public institutions like LAEDC's partners at California State University, Dominguez Hills are doing everything possible to ensure the health and safety of their students, faculty, and staff. In lieu of the typical registration fee, please donate to the CSUDH Student Emergency Fund, a source of support for students who would otherwise find it difficult to continue their education. 


Thank you in advance for your support! All gifts to the university are tax-deductible to the extent allowed by law. Please note that donating to the CSUDH Emergency Grant Fund will not automatically register you for the event. To register for the event, please continue to click the button above. 

Keynote speaker: Senator Maria Elena Durazo

Hosted by La Plaza Village Apartment Development: a public private partnership

During these unprecedented times, the future can be intimidating, but the bioscience industry provides a progressive pathway to developing treatments and cures across the disease spectrum.

 

The LAEDC is focusing on timely research to provide updated regional insights to inform the bioscience stakeholders and decisionmakers about the state of the industry including challenges, opportunities, and how a year with the pandemic will affect future growth.

© 2020 Los Angeles County Economic Development Corporation.

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Patrick Soon-Shiong, MBBCh, MSc, FRCS (C), FACS.

Patrick Soon-Shiong, M.D., a physician, surgeon, scientist, inventor, technologist and philanthropist, has devoted his career to understanding the fundamental biology driving life-threatening diseases and translating these insights into medical innovations with global impact.

 

He serves as Chairman and Chief Executive Officer of NantWorks, an ecosystem of companies with deep understandings in a wide variety of complex industries, from medical science to physics, from data to AI and from communications to mobility. 

 

Dr. Soon-Shiong was born in Port Elizabeth South Africa and received his medical degree at the University of the Witwatersrand, Johannesburg in 1975. He was the first Chinese intern granted permission to serve his internship at the Johannesburg General Hospital during the period of apartheid. Following a period in the TB clinics in East London, he left to continue his training as a surgeon at University of California, Los Angeles (UCLA). He was appointed Assistant Professor of Surgery and Assistant Professor of Medicine at UCLA, led the development of the California NanoSystems Institute and received support from NASA and NIST to develop next-generation biological materials. While at UCLA, he served as Executive Director of the UCLA Wireless Health Institute and a Professor of Microbiology, Immunology & Molecular Genetics and Professor of Bioengineering at the California NanoSystems Institute of UCLA. He currently is an Adjunct Professor of Surgery at the University of California, Los Angeles (UCLA), a visiting Professor at the Imperial College of London. Dr. Soon-Shiong currently sits on the Board of Councilors at the University of Southern California (USC) Viterbi School of Engineering.

 

Over the course of Dr. Soon-Shiong’s career, he has pioneered novel therapies for both diabetes and cancer, including the revolutionary drug Abraxane, a protein nanoparticle, which has received U.S. Food and Drug Administration (FDA) approval for the treatment of metastatic breast cancer, lung cancer and advanced pancreatic cancer in both the U.S. and E.U., published more than 100 scientific papers, and has been granted more than 400 patents worldwide for groundbreaking advancements spanning myriad fields of technology and medicine.

 

As a surgeon, Dr. Soon-Shiong performed the world’s first encapsulated human islet transplant, the first engineered islet cell transplant and the first pig-to-man islet cell transplant in patients with diabetes.

 

Dr. Soon-Shiong’s path to cancer research began while doing research for the National Aeronautics and Space Administration (NASA) that involved harnessing stem cells to make insulin. In 1991, he founded a biotechnology company to develop a novel nanoparticle anti-cancer drug with the concept of using “the tumors biology against itself.” 

 

From 1996 to 2010, Dr. Soon-Shiong served as Founder, Chairman and CEO of two global pharmaceutical companies: American Pharmaceutical Partners and Abraxis BioScience. It was during Dr. Soon-Shiong’s tenure at Abraxis that the company manufactured the world’s first protein nanoparticle drug for breast, lung and pancreatic cancer—Abraxane. In 2008, Dr. Soon-Shiong sold American Pharmaceutical Partners to Fresenius for approximately $4.6 billion and in 2010, sold Abraxis BioScience to Celgene for approximately $3.8 billion.

 

Following the sale of these two companies in 2010, Dr. Soon-Shiong established NantWorks, LLC, an ecosystem of companies with deep understandings in a wide variety of complex industries, from science to data, communication and mobility. The mission of NantWorks is to develop technologies which would have global impact on life-threatening diseases such as cancer and pandemic infectious diseases. Under the NantWorks umbrella, Soon-Shiong serves as Executive Chairman of NantKwest, a Nasdaq-listed immunotherapy company focusing on natural killer cells; Chairman and CEO of ImmunityBio, Inc., a biotechnology company focusing on vaccines and immunotherapy for cancer and infectious diseases; Chairman and CEO of NantHealth, a Nasdaq listed transformational healthcare company converging biomolecular medicine and bioinformatics with deep learning AI to empower physicians, patients, payers, pharma and researchers to transcend the traditional barriers of today's healthcare system; Chairman of NantEnergy, a privately-held company accelerating the worldwide transformation to clean, reliable energy disrupting industrial scale methods of heat production, cement and plastics manufacturing; and Owner and Executive Chairman of California Times, publisher of two of the state’s largest newspapers, the Los Angeles Times and The San Diego Union-Tribune. 

 

In January 2016, Dr. Soon-Shiong announced the formation of Cancer Breakthroughs 2020, a comprehensive collaboration of researchers, insurers, academic institutions and pharmaceutical companies to accelerate the potential of combination immunotherapy in the treatment of cancer. 

 

The Cancer Breakthroughs 2020 initiative has a goal of originating Phase 2 and 3 trials of the Nant Cancer Vaccine in multiple tumor types. By 2020, Dr. Soon-Shiong’s team have initiated over 17 investigational new drug (IND) applications demonstrating the safety and efficacy of first-in-human novel biological fusion proteins and adenovirus vaccines with complete remissions in multiple tumor types including metastatic pancreatic cancer, metastatic head & neck cancer, metastatic triple negative breast cancer, and merkel cell carcinoma.  

 

Dr. Soon-Shiong is Chairman of the Chan Soon-Shiong Family Foundation and of the Chan Soon-Shiong Institute of Molecular Medicine, a nonprofit medical research organization. In May 2017, he was appointed by House Speaker Paul Ryan to the Health Information Technology Advisory Committee, a committee established by the 21st Century Cures Act that will advise the President and his administration on health IT policy and will tackle issues with healthcare interoperability and privacy and security, while working with key stakeholders to create standards in these areas.

 

In April 2016, Dr. Soon-Shiong received the Franklin Institute Award for his visionary leadership and commitment to advancing medical and scientific research and bringing new treatment options to people with cancer. Dr. Soon-Shiong was also honored at the Vatican with the Pontifical Key Visionary Award in April 2016, which recognizes “medical innovators who change the course of history and reduce suffering on a global scale by blending visionary thinking with real action.” The Friends of the National Library of Medicine has also honored him with their Distinguished Medical Science Award. 

 

In June 2017, the Smithsonian Institute honored his work by placing Abraxane in the permanent exhibit at Smithsonian’s National Museum of American History. 

 

In June 2018, Dr. Soon-Shiong completed the purchase of the Los Angeles Times, San Diego Union-Tribune and publications under the California News Group.

 

In 2020, Dr. Soon-Shiong and his scientific team devoted their resources and scientific expertise to the development of a vaccine to address the COVID-19 pandemic. Utilizing their expertise in treating cancer, Dr. Soon-Shiong and his team took the novel approach of developing a vaccine that would induce both antibodies and T cells to clear the virus. To date, this vaccine construct which includes both the Spike (S) and Nucleocapsid (N) protein is the first-in-human subcutaneous formulation to demonstrate antibody as well as T cell immune response. In the US BARDA Operation Warp Speed sponsored Non-Human Primate (NHP) challenge study, the vaccine both as an orally room temperature stable capsule as well as a subcutaneous formulation showed 100% protection against SARS-CoV-2 challenge in all animals tested. The subcutaneous formulation has initiated clinical trials and demonstrated no serious adverse events to date. The sublingual and oral formulation will initiate Phase 1 trials shortly. With the evolution of the virus and mutations in Spike, the N + S T cell vaccine developed by ImmunityBio could provide a solution to the rapidly mutating SARS-CoV-2 virus.  By developing a room temperature oral form of the vaccine, global distribution, especially to developing countries could be achieved.

 

Born and raised during apartheid in South Africa, Dr. Soon-Shiong resides in Los Angeles California and is a citizen of the United States.

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